Monoamine Oxidase Inhibitors (MAOIs) are a class of antidepressants that have been used since the 1950s to treat various mental health conditions. They work by inhibiting the activity of monoamine oxidase enzymes, thereby increasing the levels of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. This mechanism can help alleviate symptoms of depression and anxiety.

Uses of MAOIs

MAOIs are primarily prescribed for depression, especially when other treatments have not been effective. They are particularly beneficial for atypical depression, which may present with mood reactivity, increased appetite, and excessive sleep. Beyond depression, MAOIs have been utilized in treating panic disorder, social anxiety disorder, and Parkinson's disease.

Considerations and Side Effects

While MAOIs can be effective, they require careful management due to potential interactions with certain foods and medications. Patients must adhere to dietary restrictions to avoid hypertensive crises and be cautious of drug interactions that could lead to serotonin syndrome or other adverse effects. Common side effects include dizziness, sleep disturbances, and weight gain.

If you're struggling with depression or anxiety and are interested in exploring treatment options, including MAOIs, we invite you to schedule a free discovery call with Dr. Doi. Together, you can discuss your symptoms, treatment history, and goals to develop a personalized plan aimed at achieving your mental health objectives. Take the first step towards a brighter future by reaching out today.